I'm not sure what you're trying to achieve from the motor, or what parts you're putting into it.
Generally speaking though, it's the valve train that runs into issues first - as far as RPM goes.
If you're building a motor, there's certainly no reason to not balance it beyond the factory spec if you have the money or skills to do so. However, as you noted in your above post, there are other limiting factors that I would argue play a larger part in getting RPM/HP out of a motor.
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